BIOC 5701

Enzymes

Lec 01 selected

Fundamental principles of enzyme catalysis and its regulation are examined. Topics include enzyme kinetics, enzyme inhibition and inactivation, isotope effect measurements, site-directed mutagenesis, and the active site architecture and transition state stabilization of selected enzymes. Classic and current papers in the literature are reviewed and the experimental and conceptual approaches are critically appraised.

Sections

Lecture

From the syllabus

From the Winter 2026 syllabus by Stephen L. Bearne. Open the PDF

Grading

15%First midtermSchedule lists Feb 12, 2026; assessment table lists Feb 11, 2025
15%Second midtermSchedule lists Mar 19, 2026; assessment table lists Mar 18, 2025
30%Problem setsApproximately every two weeks
40%Final exam3 hours; must pass to pass the course

Textbook

  • Enzyme Kinetics, I. H. Segel

Course rules

Missed evaluations
Notify the instructor if possible within 48 hours and submit an SDA form within three calendar days.
Make-up tests
If offered, make-up midterms are normally written within seven calendar days after the missed test.
Problem sets
Late problem sets receive zero; SDA forms are not accepted for problem sets.
Missed final
For illness, notify the coordinator or department within 48 hours and provide a medical certificate.
Final exam
Students must pass the final exam to pass the course.
Graduate presentations
Attendance at graduate student presentations is mandatory.

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