TOX 6590

The molecular mechanisms of action of carcinogens and other toxic compounds. Enzymes of biotransformation, including a detailed study of cytochrome P-450. Interactions of reactive species with DNA and other macromolecules. Offered in conjunction with TOX*4590. Extra work is required of graduate students. [Restriction(s): Credit may be obtained for only one of TOX*4590 and TOX*6590][Department(s): Department of Chemistry]