BCMB 403

This is a lecture-based course designed to provide in-depth knowledge on advanced topics in nucleic acid biochemistry. Topics include mechanistic analysis of nucleic acid metabolism; the RNA world hypothesis and theories of the origin of life; epigenetics; specificity and role of polymerases and repair pathways; replication and recombination mechanisms; RNA structural motifs and physical processing in gene expression; structure and function of non-coding RNA; silencing and micro RNA; catalytic RNA molecules; and technological applications of RNA.