BCMB 702

This course focuses on a new discipline, spanning the fields of chemistry and biology, that forms the basis of current pharmaceutical research. Chemical biology uses the techniques and tools of chemistry to study and manipulate biological systems, often using small molecules produced synthetically or derived from natural sources. Both in vitro and in vivo systems that are probed with small molecules are covered in this course. Emphasis is placed on the theoretical and experimental strategies used to design or discover molecules with useful properties, including biochemical and cell-based screens.