TOX 402

This course will provide an overview of the types of injury produced in specific organs by chemical stressors. We discuss how structural and functional changes at the molecular, cellular, tissue, and organ level can alter organ system function to produce adverse effects (e.g. disease). Students will become familiar with traditional biomarkers of organ injury as well as introduced to new approach methods in systems toxicological assessment. The course is organized into modules according to target organ systems with focus on adverse effects in mammals.